Tournament of Champions takes a story-based approach, putting players on the Pro Circuit as a new pro and protege of Chris "Jesus" Ferguson. Players test their skills at the premier Circuit Events in hopes of qualifying for the winner-take-all, invitation-only Tournament of Champions at the Rio Resort in Las Vegas. Along the way, they face-off against more top pros than ever before, including Joseph Hachem, the 2006 World Series of Poker Main Event Champion, and Jennifer Tilly, the Academy Award-nominated actress and World Series of Poker bracelet holder, among others in hopes of bringing home the Tournament of Champions trophy.